Premium GH Pept (GHRP-2) – UK Laboratory Research Grade

If your facility is looking to buy ghrp2 compounds for scientific evaluation, our GH pept inventory provides researchers with high-purity Growth Hormone Releasing Peptide-2 (Pralmorelin). As a synthetic second-generation ghrelin receptor agonist, this specialized GH pept compound acts directly on the anterior pituitary gland to stimulate endogenous growth hormone (GH) secretion in cellular and endocrinological research models.

Supplied as a stable, sterile lyophilized powder in individual 5mg and 10mg vials, every batch of our GH pept undergoes strict third-party verification via High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to guarantee consistent analytical performance.

Technical Specifications & Chemical Profile

Our reference-grade GH pept (GHRP-2) is manufactured according to solid-phase peptide synthesis (SPPS) standards:

Attribute	Analytical Specification
Product Name	GH Pept / GHRP-2 (Growth Hormone Releasing Peptide-2)
CAS Registry Number	158861-67-7
Sequence	D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH₂
Molecular Formula	C₄₅H₅₅N₉O₆
Molecular Weight	818.0 g/mol
Purity Grade	≥99.0% (Verified via HPLC & MS)
Physical Form	Sterile, white lyophilized powder / cake
Reconstitution Diluent	Bacteriostatic Water or Sterile 0.9% Sodium Chloride
Storage (Unopened)	Store desiccated at -20°C (protected from light)

Mechanism of Action & GH Pept Research Protocols

In scientific literature, this GH pept is classified under the Growth Hormone Secretagogue (GHS) family and functions through distinct biochemical pathways:

• Ghrelin Receptor Binding: This GH pept acts as a potent agonist at the Growth Hormone Secretagogue Receptor (GHS-R1a). Binding activates phospholipase C (PLC), leading to intracellular signal transduction that prompts pulsatile growth hormone release.

• Synergy with GHRH Analogues: Research indicates that co-administering GH pept compounds alongside Growth Hormone Releasing Hormone (GHRH) analogues—such as CJC-1295 or Mod GRF 1-29—produces a synergistic surge in pituitary GH release, significantly higher than either compound tested independently.

• Nitrogen Retention Studies: As a structural analogue of ghrelin, GH pept exhibits moderate ghrelin-mimicking effects on hypothalamic feeding centers, making it a primary subject of study for nitrogen retention and cellular repair models.

Reconstitution & Laboratory Protocols

To maintain molecular integrity and prevent structural shearing during preparation:

1. Equilibration: Allow the lyophilized GH pept vial to reach room temperature prior to adding diluent to minimize internal condensation.

2. Reconstitution: Using a sterile syringe, direct 1 ml to 2 ml of Bacteriostatic Water slowly down the inside glass wall of the vial.

3. Dissolution: Swirl the vial gently in a circular motion until the powder fully dissolves into a clear liquid. Do not shake vigorously, as mechanical stress can disrupt delicate peptide bonds.

4. Storage: Refrigerate reconstituted GH pept solutions between 2°C and 8°C. For long-term preservation, store liquid aliquots at -20°C to avoid repeated freeze-thaw cycles.

Frequently Asked Questions

What is the primary function of this GH pept in research?

This GH pept (GHRP-2) functions as a selective growth hormone secretagogue, binding to pituitary ghrelin receptors to trigger the natural secretion of growth hormone for analytical and cellular studies.

What is the difference between this GH pept and GHRP-6?

While both belong to the growth hormone-releasing peptide family, this GH pept (GHRP-2) exhibits higher overall potency in stimulating growth hormone release with significantly less appetite stimulation compared to GHRP-6.

What documentation is supplied when I buy GH pept online?

Every order includes access to a lot-specific Certificate of Analysis (COA), featuring HPLC traces confirming ≥99% purity and Mass Spectrometry data verifying the molecular mass of 818.0 g/mol.