Premium GW-501516 (Cardarine) – UK Research Grade

If your facility is seeking to obtain high-purity gw-501516 for metabolic, lipid oxidation, or endurance pathways research, our supply delivers certified reference-grade material. Chemically classified as a selective Peroxisome Proliferator-Activated Receptor delta ($\text{PPAR}\delta$) agonist rather than a SARM, cardarine gw 501516 is widely studied in cellular biology for its ability to shift metabolic energy preference from glucose to fatty acid oxidation.

Whether investigating AMPK pathway activation, lipid clearance mechanisms, or skeletal muscle endurance markers, our gw-501516 inventory provides $\ge 99\%$ HPLC-verified purity, comprehensive batch analytical documentation, and fast domestic UK tracked shipping.

Technical Specifications & Chemical Profile

Our reference-grade gw-501516 (cardarine gw 501516) reference material is synthesized in strict compliance with laboratory analytical standards:

Attribute	Analytical Specification
Chemical Name	GW-501516 / Cardarine (Endurobol)
IUPAC Name	2-[2-methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methyl]sulfanyl]phenoxy]acetic acid
CAS Registry Number	317318-70-0
Molecular Formula	$\text{C}_{21}\text{H}_{18}\text{F}_3\text{NO}_3\text{S}_2$
Molecular Weight	$453.5 \text{ g/mol}$
Purity Grade	$\ge 99.0\%$ (Verified via HPLC & Mass Spectrometry)
Physical Form	Crystalline solid / Lyophilized powder
Solubility Profile	Soluble in DMSO ($>20 \text{ mg/mL}$) and Ethanol; insoluble in water
Storage (Unopened)	Store desiccated at $-20^\circ\text{C}$ (protected from UV exposure)

Mechanism of Action & Research Applications

In biochemical and metabolic literature, cardarine gw 501516 operates as a potent receptor ligand with distinct pathways:

• $\text{PPAR}\delta$ Receptor Agonism: gw-501516 selectively binds to the $\text{PPAR}\delta$ nuclear receptor, inducing transcription of genes involved in cellular energy expenditure and fatty acid beta-oxidation in skeletal muscle tissue.

• AMPK Pathway Activation: Research indicates that exposure to cardarine gw 501516 stimulates AMP-activated protein kinase (AMPK), enhancing glucose uptake in muscle cells and altering mitochondrial biogenesis.

• Lipid Profile Regulation: In animal research models, activation of the $\text{PPAR}\delta$ pathway by gw-501516 has demonstrated marked reductions in plasma triglycerides and low-density lipoproteins (LDL) while elevating high-density lipoprotein (HDL) levels.

Laboratory Handling & Preparation Guidelines

To ensure compound stability and accurate experimental dosing:

1. Equilibration: Allow frozen containers of gw-501516 to reach ambient room temperature before opening to avoid atmospheric moisture absorption.

2. Solubilization: Cardarine gw 501516 is hydrophobic and insoluble in aqueous media. Dissolve raw powder in high-purity DMSO, polyethylene glycol (PEG 400), or pure ethanol.

3. Agitation: Gentle vortexing or mild heating ($<40^\circ\text{C}$) in a water bath can accelerate dissolution in organic solvents.

4. Storage Conditions: Store stock liquid solutions frozen at $-20^\circ\text{C}$ in light-protected glass containers. Avoid repeated freeze-thaw cycles.

Frequently Asked Questions

Is GW-501516 (Cardarine) classified as a SARM?

No. While frequently grouped with Selective Androgen Receptor Modulators (SARMs) in commercial shorthand, cardarine gw 501516 does not interact with androgen receptors. It is chemically defined as a selective $\text{PPAR}\delta$ agonist.

What analytical documentation accompanies GW-501516 orders?

Every batch includes access to a lot-specific Certificate of Analysis (COA) containing High-Performance Liquid Chromatography (HPLC) chromatograms verifying $\ge 99\%$ purity and Mass Spectrometry (MS) identity confirmation.

How should raw GW-501516 powder be stored long-term?

Store raw, dry gw-501516 chemical reference powder sealed under desiccated conditions at $-20^\circ\text{C}$ in a dark environment.